| Date | 1/24/2022 | |||||
| Seed | Team | Team | Team | Team | Team | Team |
| 1 | Arizona | Gonzaga | Auburn | Baylor | ||
| 2 | Houston | Villanova | Kansas | Purdue | ||
| 3 | Kentucky | LSU | Wisconsin | Duke | ||
| 4 | Illinois | Texas Tech | UCLA | Xavier | ||
| 5 | Michigan St. | Tennessee | Alabama | Ohio St. | ||
| 6 | Connecticut | Texas | USC | Providence | ||
| 7 | BYU | Loyola (Chi.) | Seton Hall | Iowa St. | ||
| 8 | Marquette | Wake Forest | North Carolina | Iowa | ||
| 9 | Colorado St. | Saint Mary’s | Indiana | San Francisco | ||
| 10 | San Diego St. | Florida | Davidson | Murray St. | ||
| 11 | Oregon | Florida St. | Miami (Fla.) | TCU | ||
| 12 | UAB | Chattanooga | Michigan | Creighton | Virginia Tech | Wyoming |
| 13 | Iona | Toledo | Vermont | South Dakota St. | ||
| 14 | Wagner | New Mexico St. | Towson | Oakland | ||
| 15 | Liberty | Princeton | South Alabama | UC-Riverside | ||
| 16 | Navy | Montana St. | Texas Southern | Longwood | Norfolk St. | Texas A&M-CC |
Best of the Rest
| 69 | Boise St. |
| 70 | Arkansas |
| 71 | Texas A&M |
| 72 | Mississippi St. |
| 73 | Cincinnati |
| 74 | Saint Louis |
| 75 | Missouri St. |
| 76 | Belmont |
The Pi-Rate Ratings 