| Home | Visitors | Spread |
| Providence | Butler | 10.5 |
| Purdue | Northwestern | 13.2 |
| Bryant | St. Francis (NY) | 10.3 |
| Niagara | Rider | 8.9 |
| Canisius | Saint Peter’s | -2.4 |
| Marquette | Xavier | -0.9 |
| Mount St. Mary’s | Central Connecticut | 8.4 |
| Purdue Fort Wayne | Youngstown St. | 1.9 |
| Evansville | Illinois St. | -2.2 |
| Marist | Fairfield | 3.7 |
| Monmouth | Manhattan | 11.1 |
| Quinnipiac | Iona | -8.9 |
| Saint Louis | Massachusetts | 9.0 |
| California | Arizona | -14.9 |
| Tulsa | Memphis | -5.7 |
| Merrimack | Wagner | -8.4 |
| Cleveland St. | Robert Morris | 10.9 |
| Indiana | Michigan | 3.7 |
| UTSA | UTEP | -6.8 |
| St. Francis (PA) | Sacred Heart | 1.9 |
| Fairleigh Dickinson | Long Island | -6.7 |
| Oregon | Washington | 10.8 |
January 23, 2022
PiRate Ratings College Basketball–Sunday, January 23, 2022
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The Pi-Rate Ratings 