| Date | 3/14/2021 | FINAL | ||||
| Seed | Team | Team | Team | Team | Team | Team |
| 1 | Gonzaga | Baylor | Illinois | Michigan | ||
| 2 | Ohio St. | Alabama | Iowa | Houston | ||
| 3 | Oklahoma St. | Arkansas | Kansas | Texas | ||
| 4 | West Virginia | Purdue | Virginia | Florida St. | ||
| 5 | Tennessee | Villanova | Creighton | Texas Tech | ||
| 6 | Colorado | USC | LSU | Missouri | ||
| 7 | BYU | Oklahoma | Oregon | Clemson | ||
| 8 | Connecticut | San Diego St. | Wisconsin | Florida | ||
| 9 | Virginia Tech | Loyola (Chi.) | Georgia Tech | North Carolina | ||
| 10 | Rutgers | St. Bonaventure | Maryland | VCU | ||
| 11 | Louisville | Michigan St. | UCLA | Syracuse | Utah St. | Drake |
| 12 | Oregon St. | Georgetown | North Texas | Winthrop | ||
| 13 | Ohio U | Liberty | UNCG | UCSB | ||
| 14 | Colgate | Morehead St. | Abilene Christian | E. Washington | ||
| 15 | Cleveland St. | Drexel | Grand Canyon | Iona | ||
| 16 | Oral Roberts | Hartford | Norfolk St. | Mount St. Mary’s | Texas Southern | Appalachian St. |
1st Four Out
| 69 | Wichita St. |
| 70 | Colorado St. |
| 71 | Saint Louis |
| 72 | Boise St. |
1st 4 Games
11 UCLA vs. 11 Drake
11 Syracuse vs. 11 Utah St.
16 Norfolk St. vs. 16 Mount St. Mary’s
16 Texas Southern vs. 16 Appalachian St.
The Pi-Rate Ratings 