| Tuesday, November, 10th |
| Time (ET) | Network | Home | Visitor | Comment |
| 7:00 PM | CBSSN | Ohio U | Akron | Should be a large OU win |
| 7:30 PM | ESPN2 | Bowling Green | Kent St. | Should be even bigger Kent St. win |
| 8:00 PM | ESPN | Buffalo | Miami (O) | Best MACtion of the evening |
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| Wednesday, November, 11th |
| Time (ET) | Network | Home | Visitor | Comment |
| 7:00 PM | CBSSN | Ball St. | Eastern Michigan | Winner has chance at winning season but not much |
| 8:00 PM | ESPNU | Northern Illinois | Central Michigan | Should be worth watching |
| 8:00 PM | ESPN | Western Michigan | Toledo | Best MACtion of the night |
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| Thursday, November 12th |
| Time (ET) | Network | Home | Visitor | Comment |
| 8:00 PM | FS1 | Boise St. | Colorado St. | Steve Addazio has CSU believing they can win |
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| Friday, November 13th |
| Time (ET) | Network | Home | Visitor | Comment |
| 7:00 PM | CBSSN | Florida Intl. | Florida Atlantic | Rivalry game could be interesting |
| 7:00 PM | FS1 | Minnesota | Iowa | Iowa has lots of dissension–players leaving |
| 7:30 PM | ESPN2 | Cincinnati | East Carolina | Bearcats need big win for playoff chances |
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| Saturday, November 14th |
| Time (ET) | Network | Home | Visitor | Comment |
| 12:00 PM | ABC | Michigan St. | Indiana | The return of the IU Cardiac Kids! Another close win??? |
| 12:00 PM | FOX | West Virginia | TCU | WVU much better at home than on road |
12:00 PM | ESPN | Missouri | Georgia | Just might be very close game |
| 12:00 PM | ESPN2 | Virginia Tech | Miami (Fla.) | Hurricanes still in ACC Championship race |
12:00 PM | ESPNU | Troy | Coastal Carolina | CCU is in the crosshairs in trap game |
| 12:00 PM | FS1 | Nebraska | Penn St. | Could this be the Hot Seat Bowl? |
| 12:00 PM | CBSSN | Marshall | Middle Tenn. | Coming up on the 50th anniversary of tragic accident |
| 12:00 PM | BTN | Rutgers | Illinois | RUNJ a favorite in Big Ten game |
| 12:00 PM | SECN | Kentucky | Vanderbilt | If you liked college football in 1958, watch this one |
| 12:00 PM | ACCN | North Carolina | Wake Forest | Best ACC game of the weekend |
| 3:30 PM | ABC | Boston College | Notre Dame | Deja vu 1993??? |
3:30 PM | ESPN | Tennessee | Texas A&M | In danger of being postponed from Covid |
| 3:30 PM | ESPN2 | Stanford | Colorado | Karl Dorrell’s new look Buffs can score |
| 3:30 PM | FOX | Arizona | USC | Trojans try to wrap up Grand Canyon State title |
3:30 PM | BTN | Maryland | Ohio St. | Might be interesting for a half |
3:30 PM | ESPNU | Navy | Memphis | Expect 80 points or more |
| 3:30 PM | CBSSN | Western Ky. | Southern Miss. | Only if you have a child playing in this game |
| 3:30 PM | ACCN | Virginia | Louisville | Second attempt to play this basketball rivalry on turf |
| 4:00 PM | FS1 | Texas Tech | Baylor | Also-ran Lone Star State battle |
6:00 PM | CBS | LSU | Alabama | Very doubtful this game gets played–LSU has 1 QB |
| 7:00 PM | FOX | Washington St. | Oregon | Cougars actually have a running game too |
| 7:00 PM | ESPN | Florida | Arkansas | Another potential Covid casualty |
| 7:00 PM | ESPN2 | Tulsa | SMU | Could become the best game of the weekend |
7:00 PM | FSN | Georgia Tech | Pittsburgh | Must win game for Pitt to have winning season |
| 7:30 PM | ABC | Michigan | Wisconsin | UM struggling on the field/UW struggling with Covid |
| 7:30 PM | ESPNU | Central Florida | Temple | Probable blowout |
| 7:30 PM | SECN | Ole Miss | South Carolina | Rebels looking good in this one |
| 7:30 PM | BTN | Purdue | Northwestern | Ironically, this is now an important BiG West game |
| 7:30 PM | ACCN | NC St. | Florida St. | Wolf Pack needs this one to be a bowl team |
10:30 PM | FOX | UCLA | Utah | Chip Kelly has reached end of usefulness in Westwood |
10:30 PM | ESPN2 | Arizona St. | California | Can Sun Devils bounce back after having hearts broken |
| 11:00 PM | FS1 | Washington | Oregon St. | Don’t count Beavers out as Pac-12 North contender |
